Application of combined gas chromatography/mass spectrometry to neurotransmitter research

The features of flexibility, sensitivity and specificity continue to make GC/MS a valuable technique for identification and quantification of neuro-transmitters and related compounds. In this report four recent examples are presented which highlight the potentials of this technique. The traditional concept that GC/MS equipment is expensive and complex to operate warrants reconsideration in light of recent manufacturing trends in automation, computerization and the introduction of cheaper bench-top models.