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Author Spotlight: Assessing Ischemic Stroke Damage Through Middle Cerebral Artery Occlusion Model
Published on: August 11, 2023
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Stroke and temporal arteritis: A study of 6 cases.
A Lago1, J I Tembl1, G Fortea1
1Servicio de Neurología, Hospital Universitario La Fe, Valencia, España.
Neurologia
|September 5, 2017
Summary
Ischaemic stroke due to temporal arteritis (giant cell arteritis) is serious and requires high suspicion for early diagnosis and treatment. New imaging techniques aid assessment, and endovascular therapy may benefit selected patients.
Area of Science:
- Neurology
- Rheumatology
- Vascular Medicine
Background:
- Ischaemic stroke secondary to temporal arteritis (giant cell arteritis) presents diagnostic and management challenges.
- A high index of suspicion is crucial for timely intervention.
Observation:
- A series of 6 patients with biopsy-proven temporal arteritis and ischaemic stroke were analyzed.
- Patients had a mean age of 68.3 years, with 50% being female and presenting with systemic symptoms.
- Both anterior and posterior circulation were affected, with MRI angiography, Doppler sonography, and PET-CT proving useful.
Findings:
- Clinical outcomes were poor, with 33% scoring ≥3 on the modified Rankin scale (including one death).
- Recurrent strokes occurred in two patients despite high-dose corticosteroids; two patients underwent angioplasty.
- Mean follow-up was 26 months.
Implications:
- Early corticosteroid treatment is vital for managing stroke in giant cell arteritis.
- Advanced diagnostic techniques improve patient assessment and treatment selection.
- Endovascular treatment is a potential therapeutic option for specific cases.
