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Updated: Feb 23, 2026

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Studying Food Reward and Motivation in Humans
Published on: March 19, 2014
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In the Hunger Games, the Winner Takes Everything
Franziska Püschel1, Cristina Muñoz-Pinedo1
1Cell Death Regulation Group, Oncobell Program, Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.
Trends in Biochemical Sciences
|September 5, 2017
Abstract:
Entosis is an atypical form of cell death that occurs when a cell engulfs and kills another cell. A recent article by Overholtzer and colleagues indicates that glucose deprivation promotes entosis. AMP-activated protein kinase (AMPK) activation in the loser cells triggers their engulfment and elimination by winner cells, which endure starvation.
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