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The developing world of DOHaD
1Department of Pediatrics,Tokai University School of Medicine,Isehara,Japan.
Journal of Developmental Origins of Health and Disease
|September 6, 2017
Summary
The Developmental Origins of Health and Disease (DOHaD) concept, originating in 1986, explains how early life events impact adult health. This review explores its evolution, current status, and future directions in biomedical science.
Area of Science:
- Biomedical Science
- Public Health
- Developmental Biology
Background:
- The Developmental Origins of Health and Disease (DOHaD) concept was introduced in 1986.
- It posits that early life exposures influence long-term health outcomes.
- The concept has gained international recognition and influenced various research fields.
Purpose of the Study:
- To review the importance of the DOHaD concept in biomedical science.
- To outline the historical development of the DOHaD concept.
- To discuss the current and future trajectory of DOHaD research.
Main Methods:
- Literature review of seminal and recent publications on DOHaD.
- Analysis of the conceptual evolution and methodological advancements.
- Synthesis of findings to project future research directions.
Main Results:
- The DOHaD concept has significantly evolved since its inception.
- Its influence has expanded across multiple scientific disciplines.
- Methodologies and understanding of early life influences have advanced.
Conclusions:
- The DOHaD concept remains crucial for understanding health and disease etiology.
- Continued research is needed to refine DOHaD principles and applications.
- Future directions should focus on interdisciplinary approaches and translational research.
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