Some regulatory aspects of thermogenesis in cold-exposed piglets

1. Thermoregulatory mechanisms were studied in weaned piglets fed ad libitum for 3 weeks at 12 or 23 degrees C. 2. Cold-adapted pigs maintained a growth rate and a carcass composition similar to the control ones, while increasing food intake by 20% (P less than 0.05). 3. Lipoprotein lipase activity was increased (P less than 0.05) by cold exposure in white adipose tissue (WAT) and heart. A large enhancement of lipogenesis was observed in WAT and to a lesser extent in the liver while WAT composition did not change significantly in the cold. 4. Cytochrome oxydase activity was increased in liver (30%), perirenal fat (40%) and interscapular muscle (75%) of cold-exposed pigs. 5. Plasma levels of thyroid hormones (TSH, T3, T4) were increased in the cold. 6. Mechanisms and locations of heat production are discussed.