Related Experiment Video
Updated: Feb 23, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
Prosthetic mitral valve paravalvular leak: A problem that requires dexterity
James W Hansen1, Gautam Gadey1, Thomas C Piemonte2
1Lahey Hospital and Medical Center, Burlington, MA, United States.
Prosthetic valve paravalvular leak (PVL) after mitral valve replacement (MVR) can cause heart failure. This study shows successful percutaneous closure of MVR PVL using the Dexterity steerable catheter.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Medical Device Technology
Background:
- Prosthetic valve paravalvular leak (PVL) is a frequent complication following surgical valve replacement, potentially causing significant patient morbidity.
- Patients with significant mitral valve replacement (MVR) PVL often exhibit heart failure symptoms, elevated filling pressures, or hemolytic anemia.
- Percutaneous closure is the preferred treatment for significant MVR PVL.
Observation:
- Percutaneous closure of MVR PVL presents technical challenges due to procedural anatomy, patient comorbidities, and defect location.
- The Dexterity catheter, a semi-rigid steerable device with dual articulation and 360-degree flex, offers coaxial positioning to the PVL.
- This approach was utilized in our laboratory for MVR PVL repair.
Findings:
- Successful percutaneous closure of MVR PVL was achieved in presented cases.
- The Dexterity catheter facilitated coaxial alignment with the paravalvular defects.
- The steerable nature of the catheter aided in navigating complex anatomy.
Implications:
- The Dexterity catheter represents a valuable tool for interventional cardiologists performing complex percutaneous PVL closures.
- This technique may improve outcomes for patients with MVR PVL.
- Further studies could explore the broader application and long-term efficacy of this device in PVL repair.
Related Concept Videos
Mitral Stenosis III: Medical Management
Mitral Valve Prolapse I: Introduction
Mitral Valve Prolapse II: Assessment and Management
Mitral Regurgitation III: Medical Management
Mitral Stenosis I: Introduction
Mitral Stenosis II: Clinical features and Diagnostic Tests

