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The Nucleosome Core Particle

The Nucleosome Core Particle

Nucleosomes are the DNA-histone complex, where the DNA strand is wound around the histone core. The histone core is an octamer containing two copies of H2A, H2B, H3, and H4 histone proteins.
The paradox
Nucleosomes, paradoxically, perform two opposite functions simultaneously. On the one hand, their main responsibility is to protect the delicate DNA strands from physical damage and help achieve a higher compaction ratio. While on the other hand, they must allow polymerase enzymes to access DNA...

The Nucleosome Core Particle

The Nucleosome Core Particle

Nucleosomes are the DNA-histone complex, where the DNA strand is wound around the histone core. The histone core is an octamer containing two copies of H2A, H2B, H3, and H4 histone proteins.
Nucleosomes, paradoxically, perform two opposite functions simultaneously. On the one hand, their primary aim is to protect the delicate DNA strands from physical damage and help achieve a higher compaction ratio. On the other hand, they must allow polymerase enzymes to access histone-bound DNA during...

Pulmonary Tuberculosis I

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...

Pulmonary Tuberculosis II

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
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Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...

Pulmonary Tuberculosis V

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
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Other Pulmonary Disorders

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.

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Related Experiment Video

Updated: Jan 31, 2026

Emergency Undocking in Robotic Surgery: A Simulation Curriculum

Emergency Undocking in Robotic Surgery: A Simulation Curriculum

Published on: May 20, 2018

Core curriculum illustration: pulmonary laceration.

Daniel Carson¹, Rachael Edwards²

¹University of Washington School of Medicine, Seattle, WA, USA.

Emergency Radiology

|September 7, 2017

Summary

This series presents emergency radiology cases to boost engagement with online educational resources. Explore more cases and study recommendations on the ASER website.

Keywords:

Chest trauma Core curriculum Pneumatocele Pulmonary laceration

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Last Updated: Jan 31, 2026

Emergency Undocking in Robotic Surgery: A Simulation Curriculum

Emergency Undocking in Robotic Surgery: A Simulation Curriculum

Published on: May 20, 2018

Mechanical Ventilation Boot Camp Curriculum

Mechanical Ventilation Boot Camp Curriculum

Published on: March 12, 2018

Controlled Cervical Laceration Injury in Mice

Controlled Cervical Laceration Injury in Mice

Published on: May 9, 2013

Area of Science:

Radiology
Medical Education

Background:

The American Society of Emergency Radiology (ASER) offers a bank of online educational cases.
This series aims to increase the utilization of these valuable resources.

Observation:

Each publication issue features one case from the online bank.
This marks the 44th installment in the ongoing series.

Findings:

The series highlights diverse emergency radiology cases.
Online case modules are designed for learning and review.

Implications:

Increased interest and use of ASER's online educational materials are anticipated.
Physicians can access comprehensive study recommendations and core curriculum information online.