Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Treating extrapyramidal reactions: some current issues.

A J Gelenberg

    The Journal of Clinical Psychiatry
    |September 1, 1987
    PubMed
    Summary

    Antipsychotic drugs can cause movement disorders like acute dystonia and Parkinson's syndrome. Prophylactic antiparkinson drugs and lower antipsychotic doses may reduce these risks, while propranolol shows promise for akathisia treatment.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Counterpoint : psychopharmacology supervision.

    Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry·2014
    Same author

    Open-label sildenafil treatment of partial and non-responders to double-blind treatment in men with antidepressant-associated sexual dysfunction.

    International journal of impotence research·2006
    Same author

    Randomized dose-ranging pilot trial of omega-3 fatty acids for postpartum depression.

    Acta psychiatrica Scandinavica·2006
    Same author

    Bipolar disorder in women: reproductive events and treatment considerations.

    Acta psychiatrica Scandinavica·2005
    Same author

    Citalopram as adjunctive therapy in bipolar depression.

    The Journal of clinical psychiatry·2002
    Same author

    Can lithium help to prevent suicide?

    Acta psychiatrica Scandinavica·2001

    Area of Science:

    • Neuroscience
    • Pharmacology
    • Psychiatry

    Background:

    • Extrapyramidal symptoms (EPS) are common side effects of antipsychotic medications.
    • These reactions include acute dystonias, akathisia, Parkinsonism, and tardive dyskinesia.
    • Managing EPS is crucial for patient adherence and treatment outcomes.

    Purpose of the Study:

    • To review current research on the management of antipsychotic-induced extrapyramidal reactions.
    • To highlight emerging treatments and prophylactic strategies for EPS.
    • To discuss the prevalence and risks associated with tardive dyskinesia.

    Main Methods:

    • Literature review of recent studies on EPS management.
    • Analysis of treatment efficacy for various extrapyramidal symptoms.
    • Examination of risk factors and incidence rates for tardive dyskinesia.

    Main Results:

    • Prophylactic antiparkinson drugs may decrease acute dystonia incidence in high-risk patients.
    • Lower antipsychotic doses can reduce EPS risk and side effects.
    • Beta-blockers, such as propranolol, are a new treatment option for akathisia.
    • Maintenance antiparkinsonian therapy is often required during long-term antipsychotic treatment.
    • Tardive dyskinesia has no effective treatment, with a growing prevalence (3-4% annual incidence), particularly in the elderly and those with affective disorders.

    Conclusions:

    • Effective management strategies exist for some EPS, including prophylactic treatments and dose adjustments.
    • New therapeutic options like propranolol offer hope for akathisia.
    • Tardive dyskinesia remains a significant challenge, necessitating further research and preventative measures.
    • Clinicians must remain vigilant for EPS and related syndromes like tardive dystonia.

    Related Experiment Videos