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[Flavonoids from Picris davurica].

Qiao Chen1, Na Guo1, Nan Xu1

  • 1School of pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian 116600, China.

Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica
|September 7, 2017
PubMed
Summary
This summary is machine-generated.

Eleven compounds were isolated from Picris davurica, including eight novel compounds for the genus. These findings expand the knowledge of bioactive compounds in medicinal plants.

Keywords:
Picris davuricachemical constituentsflavone glucosideisoetin

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Area of Science:

  • Phytochemistry
  • Natural Product Chemistry
  • Pharmacognosy

Background:

  • Picris davurica is recognized for its anti-inflammatory properties.
  • The chemical constituents of Picris davurica are not fully elucidated.
  • Identifying novel compounds can lead to new therapeutic agents.

Purpose of the Study:

  • To isolate and identify compounds from the anti-inflammatory extract of Picris davurica.
  • To characterize novel compounds from the Picris genus.

Main Methods:

  • Column chromatography using HP20 macroporous resin, MCI, Sephadex LH-20, and ODS.
  • Structure elucidation using Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (MS) data.

Main Results:

  • Eleven compounds were successfully isolated and identified.
  • Eight of the isolated compounds (1-8) were reported from the genus Picris for the first time.
  • Compounds 1-8 represent novel chemical entities within the Picris genus.

Conclusions:

  • The study successfully identified eleven compounds from Picris davurica.
  • This research contributes new knowledge to the phytochemistry of the Picris genus.
  • The identified compounds may hold potential for further pharmacological investigation.