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Related Concept Videos

Vitamins01:30

Vitamins

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Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
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The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
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Connective tissue develops from the mesoderm of a developing embryo and consists of cells, fibers, and ground substance: a gel-like material containing large complexes of carbohydrates and proteins. Connective tissue was first identified as a separate tissue family in the 18th century, and Johannes Peter Muller coined the term connective tissue.
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Sulfur is an essential element in biological systems, contributing to synthesizing key biomolecules, including amino acids such as cysteine and methionine, and cofactors such as coenzyme A and biotin. Microorganisms primarily assimilate sulfur as sulfate (SO₄²⁻) from the environment, which must undergo a series of biochemical transformations before it can be incorporated into cellular components. As sulfate is highly oxidized, it must undergo assimilatory sulfate reduction to...
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Related Experiment Video

Updated: Feb 23, 2026

Author Spotlight: Unveiling the Pathway Linking Obesity to Autoimmune Inflammation in Multiple Sclerosis
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Is there a Link between Vitamin B and Multiple Sclerosis?

Natalie Nemazannikova1, Kathleen Mikkelsen1, Lily Stojanovska1

  • 1Centre for Chronic Disease, College of Health and Biomedicine, Victoria University, Melbourne, Australia.

Medicinal Chemistry (Shariqah (United Arab Emirates))
|September 7, 2017
PubMed
Summary

Vitamin B complex, including vitamin B12, shows promise in combating demyelination in multiple sclerosis (MS) by reducing inflammation and aiding remyelination. Further research is needed to confirm its therapeutic potential for MS patients.

Keywords:
CobalaminEAEfolatemultiple sclerosisniacinpantothenic acidriboflavinthiaminvitamin B

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Area of Science:

  • Neuroscience
  • Biochemistry
  • Immunology

Background:

  • Multiple sclerosis (MS) is characterized by demyelination, damaging the myelin sheath and impairing neuronal signal transmission.
  • Both MS and deficiencies in vitamin B complex can lead to severe myelin degeneration.
  • Common symptoms of vitamin B complex deficiency include fatigue, oxidative stress, inflammation, and demyelination.

Purpose of the Study:

  • To discuss the role of the vitamin B complex (B1, B2, B3, B4, B5, B6, B7, B9, B12) in multiple sclerosis (MS).
  • To highlight the specific involvement of vitamin B12 (cobalamin) in methylation, myelination, and remyelination processes relevant to MS.
  • To explore the potential of vitamin B complex in reversing MS symptoms.

Main Methods:

  • Literature review and discussion of existing research on vitamin B complex and MS.
  • Analysis of the biochemical and neurological roles of individual vitamin B members in myelin health.
  • Examination of the anti-inflammatory and remyelinating properties of vitamin B complex.

Main Results:

  • Vitamin B complex members exhibit promising anti-inflammatory and remyelinating attributes.
  • Vitamin B12 plays a crucial role in methylation and myelination, with potential for MS symptom reversal.
  • Current clinical evidence is limited but suggests a beneficial role for vitamin B complex in MS.

Conclusions:

  • Larger clinical studies are urgently required to validate the efficacy of vitamin B supplementation in MS.
  • Investigating vitamin B supplementation, alone or in combination therapies, is crucial for MS prevention or reversal.
  • Optimizing vitamin B levels may improve the quality of life for individuals with multiple sclerosis.