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Updated: Feb 23, 2026

Author Spotlight: Advancing Syphilis Research — Innovations in Treponema pallidum Cultivation and Genetic Engineering
Published on: January 24, 2025
Secondary syphilis: The great imitator can't be forgotten
Clarissa Prieto Herman Reinehr1, Célia Luiza Petersen Vitello Kalil2, Vinícius Prieto Herman Reinehr3
1MD, Dermatologist, Member of the Brazilian Society of Dermatology, Master's Student at the Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Abstract:
Syphilis is an infection caused by Treponema pallidum, mainly transmitted by sexual contact. Since 2001, primary and secondary syphilis rates started to rise, with an epidemic resurgence. The authors describe an exuberant case of secondary syphilis, presenting with annular and lichen planus-like lesions, as well as one mucocutaneous lesion. Physicians must be aware of syphilis in daily practice, since the vast spectrum of its cutaneous manifestations is rising worldwide.
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