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Diffuse parenchymal lung disease with micro aspirations in presence of hiatal hernia

Rishitha Yelisetti1, Areig Awad1, Anand Kaji1

  • 1Department of Internal Medicine, St. Francis Medical Center, Trenton, NJ, United States.

Respiratory Medicine Case Reports
|September 8, 2017
PubMed

Insights

Gastroesophageal reflux and microaspiration are increasingly linked to idiopathic pulmonary fibrosis (IPF). Treating hiatal hernia may reduce microaspirations, potentially benefiting IPF patients.

Area of Science:

  • Pulmonary Medicine
  • Gastroenterology

Background:

  • Investigating the controversial link between gastroesophageal reflux, microaspiration, and idiopathic pulmonary fibrosis (IPF).
  • Examining the role of hiatal hernia in exacerbating microaspiration in IPF pathogenesis.

Observation:

  • Increasing evidence over the last decade supports a connection between gastroesophageal reflux, microaspiration, and IPF.
  • Hiatal hernia presence is observed to propagate microaspirations.

Findings:

  • Gastroesophageal reflux and subsequent microaspiration are implicated in the development or progression of IPF.
  • Hiatal hernia significantly contributes to the microaspiration process in individuals with or at risk for IPF.

Implications:

  • Surgical management of hiatal hernia may be a crucial therapeutic strategy for IPF.
  • Further research into reflux and aspiration as IPF drivers could lead to novel treatment approaches.
Keywords:
Diffuse parenchymal lung diseaseHiatal herniaMicro aspirations

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