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Experiments for the Development of a Steerable Microcatheter.

Yoshitaka Inaba1, Yasuaki Arai2, Miyuki Sone2

  • 1Department of Diagnostic and Interventional Radiology, Aichi Cancer Center Hospital, 1-1 Kanokoden, Chikusa-ku, Nagoya, Aichi, 464-8681, Japan. 105824@aichi-cc.jp.

Cardiovascular and Interventional Radiology
|September 8, 2017
PubMed
Summary

This study shows a new steerable microcatheter significantly reduces procedure time and contrast agent use in animal models. The device demonstrated excellent functionality for potential clinical application.

Keywords:
Animal studyDevelopment experimentSteerable microcatheter

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Area of Science:

  • Medical Devices
  • Interventional Radiology
  • Vascular Surgery

Background:

  • Microcatheters are crucial tools in minimally invasive vascular procedures.
  • Developing steerable microcatheters enhances procedural efficiency and patient outcomes.
  • Current microcatheters may have limitations in navigating complex arterial anatomies.

Purpose of the Study:

  • To evaluate the practicality of a novel steerable microcatheter developed by Sumitomo Bakelite.
  • To assess the device's performance in animal models for potential clinical introduction.

Main Methods:

  • A steerable microcatheter (2.4F/2.9F OD, 0.021" ID, 125 cm length) with a tip-steering mechanism was tested.
  • Five interventional radiologists performed procedures in a porcine model, navigating hepatic and iliac arteries.
  • Performance metrics included procedure time, fluoroscopy time, contrast volume, guidewire use, and post-procedure vascular damage assessment.

Main Results:

  • The steerable microcatheter, used without a guidewire, significantly reduced procedure time (43.0-75.2%) and contrast agent usage (38.2-52.3%).
  • Fluoroscopy time also showed a tendency for reduction (5.1-74.1%) compared to conventional straight microcatheters.
  • No significant vascular damage was observed in the renal arteries following catheter insertion with either device.

Conclusions:

  • Animal experiments validated the steerable microcatheter's functionality for commercial development.
  • The device offers improved efficiency and safety profiles for intravascular procedures.
  • This steerable microcatheter shows promise as a valuable tool in interventional radiology.