[Prognostic factors in uveitis].

Area of Science:

• Ophthalmology
• Immunology
• Retinal Diseases

Background:

• Uveitis is a significant cause of vision loss globally.
• Identifying prognostic factors is crucial for managing uveitis patients and preventing severe visual impairment.

Purpose of the Study:

• To evaluate prognostic factors associated with vision loss in patients diagnosed with uveitis.
• To determine the prevalence of severe vision loss among uveitis patients.

Main Methods:

• A retrospective study of 89 uveitis patients (139 eyes) at a Moroccan teaching hospital over 5 years.
• Data collected included demographics, uveitis type, etiology, and complications.
• Statistical analysis, including multivariate logistic regression, was used to identify prognostic factors.

Main Results:

• 59% of eyes had final visual acuity (VA) of 1/10 or less.
• Posterior uveitis and panuveitis were strongly associated with poor final VA (P<0.001).
• Cystoid macular edema (CME), epiretinal membrane (ERM), macular scarring, and optic atrophy were identified as significant prognostic factors for severe vision loss (P<0.05).

Conclusions:

• A high percentage of uveitis patients experience significant vision loss.
• Posterior segment involvement (panuveitis, posterior uveitis), CME, and ERM are critical risk factors for poor visual outcomes in uveitis.
• Early identification and management of these complications are essential for preserving vision.