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Updated: Feb 23, 2026
A Model for Perineural Invasion in Head and Neck Squamous Cell Carcinoma
Published on: January 5, 2017
Clinicopathologic factors associated with recurrence in parotid carcinoma
Dong Hoon Lee1, Tae Mi Yoon1, Joon Kyoo Lee1
1Chonnam National University, Medical School, Department of Otolaryngology-Head and Neck Surgery, Hwasun, South Korea; Chonnam National University, Hwasun Hospital, Hwasun, South Korea.
Introduction:
Parotid carcinomas have varying histological types and diverse biologic behaviors. Establishing an adequate treatment plan and predicting recurrence is important.
Objective:
To analyze the risk factors associated with recurrence in our 5 year experience with 30 cases of primary parotid carcinoma undergoing surgery at a single institute.
Methods:
From January 2009 to December 2013, 30 patients with surgical treatment of parotid carcinoma were identified based on their medical records.
Results:
The 30 patients were comprised of 17 males and 13 females. Among 11 patients with T4 tumors, seven patients had recurrence. Among seven patients with cervical nodal metastasis, all patient except one had recurrence. Clinically late stages (stage III and IV) showed more common recurrence than early stage (stage I and II) lesions. Lymphovascular invasion was seen in 5 patients, and all patients had recurrence. Among 11 patients with extracapsular spread, 7 patients had recurrence. In 17 patients with high grade carcinomas, ten patients had recurrence. In 13 patients with low grade carcinomas, no patients experienced recurrence.
Conclusion:
T- and N-stage, clinical stage, lymphovascular invasion, extracapsular spread, and histopathologic grade correlate significantly with recurrence in parotid carcinoma.
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