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Related Concept Videos

Sutures of the Skull01:22

Sutures of the Skull

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The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
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Cranial Bones: Superior and Posterior View01:14

Cranial Bones: Superior and Posterior View

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The superior view of the cranium shows the frontal and paired parietal bones.
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
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Related Experiment Video

Updated: Feb 23, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

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Lesson to be remembered from a skull base tumor.

C Briet1, F Bernard2, P Rodien1

  • 1Institut Mitovasc, unité CNRS 6214/Inserm1083, université d'Angers, 49100 Angers, France; Service d'endocrinologie diabétologie nutrition, centre de référence des maladies rares de la réceptivité hormonale, CHU d'Angers, Angers, France.

Neuro-Chirurgie
|September 9, 2017
PubMed
Summary

Giant prolactinomas have an unknown natural history. This case reveals a microprolactinoma growing into a giant adenoma over 12 years, highlighting the need for vigilance with invasive microadenomas.

Area of Science:

  • Endocrinology
  • Neurosurgery
  • Oncology

Background:

  • The natural history of giant prolactinomas remains largely unknown.
Keywords:
Pituitary adenomaProlactinomaSkull base tumor

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  • Spontaneous enlargement of pituitary adenomas, particularly from microadenomas to giant adenomas, is poorly documented.
  • Giant adenomas can present as skull base tumors, necessitating differential diagnosis.