Related Experiment Video
Updated: Feb 23, 2026
Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
Lesson to be remembered from a skull base tumor
C Briet1, F Bernard2, P Rodien1
1Institut Mitovasc, unité CNRS 6214/Inserm1083, université d'Angers, 49100 Angers, France; Service d'endocrinologie diabétologie nutrition, centre de référence des maladies rares de la réceptivité hormonale, CHU d'Angers, Angers, France.
Giant prolactinomas have an unknown natural history. This case reveals a microprolactinoma growing into a giant adenoma over 12 years, highlighting the need for vigilance with invasive microadenomas.
Area of Science:
- Endocrinology
- Neurosurgery
- Oncology
Background:
- The natural history of giant prolactinomas remains largely unknown.
- Spontaneous enlargement of pituitary adenomas, particularly from microadenomas to giant adenomas, is poorly documented.
- Giant adenomas can present as skull base tumors, necessitating differential diagnosis.
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