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Cellular and Molecular Mechanisms of Diabetic Atherosclerosis: Herbal Medicines as a Potential Therapeutic Approach

Jinfan Tian1, Yanfei Liu2, Yue Liu3

  • 1Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China.

Oxidative Medicine and Cellular Longevity
|September 9, 2017
PubMed

Insights

Diabetic atherosclerosis is a growing concern for both type 1 and type 2 diabetes patients. This review explores herbal therapies as potential treatments for this complex cardiovascular condition.

Area of Science:

  • Cardiovascular Medicine
  • Endocrinology
  • Pharmacology

Background:

  • Diabetes mellitus (type 1 and type 2) significantly elevates the risk of severe coronary atherosclerosis.
  • The precise cellular and molecular pathways driving diabetic atherosclerosis remain incompletely understood.
  • Effective prevention and treatment strategies for diabetic atherosclerosis are still under development.

Purpose of the Study:

  • To review the current understanding of diabetic atherosclerosis.
  • To explore the potential of herbal compounds as therapeutic agents for diabetic atherosclerosis.

Main Methods:

  • Literature review of studies on diabetes mellitus, atherosclerosis, and herbal medicine.
  • Analysis of cellular and molecular mechanisms involved in diabetic atherosclerosis.
  • Synthesis of findings on the efficacy of various herbs in preclinical and clinical studies.

Main Results:

  • Herbal medicines show promise in addressing multiple facets of diabetic atherosclerosis.
  • Specific herbs may offer benefits by targeting inflammation, oxidative stress, and lipid metabolism.
  • Further research is needed to validate the clinical application of these herbal agents.

Conclusions:

  • Herbal therapies represent a potential avenue for managing diabetic atherosclerosis.
  • Targeted research into herbal compounds could lead to novel treatment strategies.
  • Integrating herbal medicine into diabetes care may improve cardiovascular outcomes.

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