Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

3.9K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
3.9K
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

287
Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
287
Cancer Prevention02:59

Cancer Prevention

8.2K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
8.2K
Aging01:26

Aging

885
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
885
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

257
Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
257
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

308
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
308

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Prone-Transpsoas Approach for Single-Position Lateral Corpectomy: A Case Series.

Brain sciences·2026
Same author

Evaluating the Use of Large Language Models in Improving the Readability of Online Patient Education Materials for Peripheral Nerve Surgery.

Healthcare (Basel, Switzerland)·2026
Same author

Glioma-intrinsic MAPK/ERK signaling promotes immunotherapy efficacy through T cell infiltration and interferon responses.

Nature communications·2026
Same author

Higher social vulnerability is associated with lower rates of peripheral nerve decompression surgery.

Clinical neurology and neurosurgery·2026
Same author

Efficacy and Descriptive Safety Assessment of Programmed Cell Death Protein-(Ligand) 1 Inhibitors Plus Chemotherapy as First-Line Treatment for Gastric and Gastroesophageal Junction Cancer in Asian and Non-Asian Patients: A Meta-Analysis.

Gastro hep advances·2026
Same author

Pancreatic cancer.

Nature reviews. Disease primers·2026

Related Experiment Videos

Nutrition and Aging: a Practicing Oncologist's Perspective.

Rishi Jain1,2, Efrat Dotan3

  • 1Department of Hematology/Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA, 19111, USA.

Current Oncology Reports
|September 9, 2017
PubMed
Summary
This summary is machine-generated.

Malnutrition significantly impacts cancer patients, especially older adults, due to aging factors. Early identification and intervention using comprehensive tools and novel approaches are crucial for better outcomes.

Keywords:
AgingCachexiaElderlyMalnutritionNutritionObesityOvernutrition

Related Experiment Videos

Area of Science:

  • Oncology
  • Geriatrics
  • Nutritional Science

Background:

  • Malnutrition is prevalent in cancer patients, leading to poor prognosis and reduced treatment tolerance.
  • Older adults with cancer face heightened malnutrition risk due to age-related changes (sensory, physical, psychosocial).

Purpose of the Study:

  • To highlight the importance of addressing nutritional concerns in older cancer patients.
  • To emphasize early identification and intervention strategies for malnutrition in this population.

Main Methods:

  • Discusses the limitations of traditional malnutrition markers (BMI, weight loss, albumin).
  • Advocates for comprehensive screening tools and emerging digital technologies for nutritional assessment.
  • Explores conventional nutritional support alongside novel nutraceutical and anti-cachexia therapies.

Main Results:

  • Comprehensive screening tools can improve early detection of eating pattern disruptions.
  • Digital technologies show promise in enhancing nutritional assessment.
  • Integrated approaches combining conventional and novel therapies may reverse malnutrition-associated body composition changes.

Conclusions:

  • Geriatric-specific nutrition research is vital for guiding interventions in older cancer patients.
  • Addressing nutritional challenges is essential for both advanced cancer and survivorship care.
  • Proactive nutritional management can improve treatment tolerance and cancer prognosis.