Reproducibility and normal values of static pupil diameters

Area of Science:

• Ophthalmology
• Optometry
• Biomedical Engineering

Background:

• Pupil diameter is a critical biometric parameter influenced by age and illumination.
• Accurate measurement of pupil size is essential for various clinical and research applications.
• Infrared pupillometry offers a non-invasive method for assessing pupillary responses.

Purpose of the Study:

• To determine normative static pupil diameter values using the PupilX infrared pupillometer.
• To evaluate the reproducibility of pupil diameter measurements obtained with the PupilX device.
• To investigate age and light-related variations in pupil size.

Main Methods:

• 91 participants with normal eyes underwent binocular infrared pupillometry using PupilX.
• Pupil diameters were measured under scotopic (0 lx), mesopic (1 lx), and photopic (16 lx) illumination.
• Each measurement was repeated five times to assess device repeatability.

Main Results:

• Mean pupil diameters were 6.5 mm (scotopic), 5.5 mm (mesopic), and 4.03 mm (photopic).
• No significant difference in pupil diameter was observed between left and right eyes.
• The PupilX device exhibited high repeatability, with unsigned anisocoria consistently below 0.3 mm and overall repeatability better than 0.2 mm.

Conclusions:

• The study provides valuable reference data for normal pupil diameters measured with the PupilX digital pupillometer.
• These findings contribute to understanding age and light-dependent changes in pupil size.
• The PupilX device is a reliable tool for reproducible pupil diameter measurements.