Ocular perfusion pressure control during pars plana vitrectomy: testing a novel device.

Area of Science:

• Ophthalmology
• Surgical Technology
• Medical Devices

Background:

• Pars plana vitrectomy (PPV) requires careful management of intraocular pressure (IOP) and ocular perfusion.
• Maintaining adequate mean ocular perfusion pressure (MOPP) is crucial for preventing intraoperative complications during PPV.

Purpose of the Study:

• To evaluate the efficacy of a new device designed to regulate infusion pressure based on real-time MOPP during PPV.
• To assess the device's ability to maintain target MOPP and control IOP fluctuations.

Main Methods:

• A novel system measured mean arterial pressure (MAP) and IOP to calculate MOPP in real-time.
• 36 patients undergoing PPV were divided into two groups: Control ON (device adjusted IOP when MOPP < 30 mmHg) and Control OFF (no adjustment).

Main Results:

• The Control ON group exhibited significantly lower average intraoperative IOP (30.5 mmHg) compared to the Control OFF group (35.9 mmHg).
• Higher MOPP was observed in the Control ON group (56.4 mmHg) versus the Control OFF group (49.7 mmHg).
• The Control ON group spent significantly less time with MOPP below 30 mmHg and 10 mmHg.

Conclusions:

• The MOPP-based infusion control device effectively lowered intraoperative IOP and increased MOPP during PPV.
• The device successfully prevented critical drops in MOPP and spikes in IOP, enhancing surgical safety.