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[Sepsis masquerading as delirium].

A Seifert1, C S Hartog2,3, J Zweigner4

  • 1Klinik für Anästhesie, Intensivmedizin und Schmerztherapie, Paracelsus-Klinik Zwickau, Zwickau, Deutschland.

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Summary
This summary is machine-generated.

A previously healthy patient developed severe symptoms, initially misdiagnosed. Prompt intensive care unit admission and sepsis treatment for Listeria infection led to complete recovery, highlighting the importance of considering septic encephalopathy.

Keywords:
Altered personalityEmergencyListeriosisSepsis-related organ failureSeptic encephalopathy

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Area of Science:

  • Infectious Diseases
  • Neurology
  • Critical Care Medicine

Background:

  • Delirium and altered personality in previously healthy individuals can be challenging to diagnose.
  • Initial misdiagnosis as bacterial meningitis and alcohol withdrawal delayed appropriate treatment.
  • Rapid deterioration despite standard meningitis protocols suggested an alternative critical illness.

Observation:

  • A 60-year-old patient presented with severe headache, fever, and personality changes, initially treated for bacterial meningitis.
  • Despite antibiotics, the patient's condition worsened, showing profound delirium and tachypnea, prompting suspicion of sepsis-associated organ failure.

Findings:

  • Blood cultures confirmed Listeria infection, a rare cause of bacterial meningitis and sepsis.
  • The patient's rapid deterioration highlighted the importance of considering septic encephalopathy in unexplained delirium.

Implications:

  • Unexplained delirium or altered personality in patients warrants immediate consideration of septic encephalopathy.
  • Early intensive care unit admission and prompt initiation of sepsis treatment are vital for favorable outcomes in suspected cases.