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Updated: Feb 23, 2026

Surgical Approach to Full Soft Tissue Face Allograft Procurement for Vascularized Composite Allotransplantation
Published on: December 30, 2025
Role of Facial Vascularized Composite Allotransplantation in Burn Patients
Deepak Bharadia1, Indranil Sinha2, Bohdan Pomahac3
1Division of Plastic and Reconstructive Surgery, Department of Surgery, UCSF School of Medicine, University of California, San Francisco, Box 0470, 505 Parnassus, San Francisco, CA 94143, USA.
Abstract:
Face transplantation can provide improved quality of life to patients with extensive burn injuries. Facial vascularized composite allotransplantation (VCA) offers a new paradigm of treatment options, serving as a powerful reconstructive tool to restore facial form and function. Although currently facial VCA patients must follow a lifelong regimen of immunosuppression medications and suffer a risk of rejection, in properly selected patients, facial VCA can be a transformative operation and can improve quality of life. Research efforts continue to optimize immunosuppression and surgical technique and serve as evidence of the procedure's growing role in reconstructive surgery for critically injured patients.

