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Candida auris: An emerging multidrug-resistant pathogen

David Sears1, Brian S Schwartz1

  • 1Division of Infectious Diseases, University of California, San Francisco, USA.

International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases
|September 11, 2017
PubMed

Insights

Candida auris is a difficult-to-identify, multidrug-resistant fungus causing invasive infections in hospitalized patients. Aggressive infection control is crucial to prevent the spread of this emerging pathogen.

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Antimicrobial Resistance

Background:

  • Candida auris is an emerging multidrug-resistant fungal pathogen.
  • It poses a significant threat, causing invasive infections in hospitalized individuals with comorbidities.
  • Traditional identification methods can be challenging for C. auris.

Purpose of the Study:

  • To highlight the challenges in identifying and treating Candida auris infections.
  • To emphasize the importance of infection control measures against C. auris outbreaks.
  • To discuss the role of echinocandins in C. auris treatment and the emergence of resistance.

Main Methods:

  • Review of current literature on Candida auris.
  • Analysis of diagnostic challenges.
  • Assessment of treatment strategies and resistance patterns.

Main Results:

  • Candida auris exhibits multidrug resistance, complicating treatment options.
  • Echinocandins are primary treatments, but resistance can occur.
  • Nosocomial outbreaks of C. auris have been documented globally.

Conclusions:

  • Effective identification and treatment of C. auris are critical.
  • Antifungal resistance in C. auris necessitates vigilant monitoring.
  • Strict infection control protocols are essential to curb transmission and outbreaks.
Keywords:
Candida aurisHealthcare-associatedInfection controlMultidrug-resistanceOutbreak

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