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Solubility of Hydrophobic Compounds in Aqueous Solution Using Combinations of Self-assembling Peptide and Amino Acid
Published on: September 20, 2017
Syntheses and effectiveness of functional peptide-based RAFT agents
Chao Chen1, Fanxing Kong, Xiaohu Wei
1Beijing Advanced Innovation Center for Soft Matter Science and Engineering, College of Materials Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China. thangsh@mail.buct.edu.cn.
Abstract:
In this study, a series of functional peptide-based RAFT agents were designed and synthesized by the solid-phase supported peptide synthesis method. These novel RAFT agents have enabled chemists to make well-defined peptide-polymer conjugates with complicated topological structures. Additionally, our results have shown an unexpected reaction that takes place during these syntheses, and the conversion of a nitrile group to a carboxamide group has been evidently elucidated and unambiguously confirmed.

