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SET-LRP in the Neoteric Ethyl Lactate Alcohol
Adrian Moreno1, Diego Garcia1, Marina Galià1
1Laboratory of Sustainable Polymers, Department of Analytical Chemistry and Organic Chemistry, University Rovira i Virgili , Tarragona, Spain.
Ethyl lactate (EtLa) is a green solvent suitable for Atom Transfer Radical Polymerization (ATRP) techniques like SET-LRP. It enables the synthesis of functional polyacrylates, expanding green chemistry applications in biomaterials.
Area of Science:
- Polymer Chemistry
- Green Chemistry
Background:
- Ethyl lactate (EtLa) is a biodegradable and eco-friendly solvent derived from biological sources.
- Its properties, including dissolving various monomers and mediating copper-catalyzed reactions, make it a potential candidate for controlled polymerization techniques.
Purpose of the Study:
- To evaluate ethyl lactate as a green solvent for Surface-Initiated Atom Transfer Radical Polymerization (SET-LRP).
- To synthesize hydrophilic and hydrophobic polyacrylates with controlled chain-end functionality using EtLa as a solvent.
Main Methods:
- Utilized Cu(0) wire catalysis for SET-LRP.
- Employed ethyl lactate as the solvent system.
- Synthesized polyacrylates with precise chain-end functionality.
Main Results:
- Ethyl lactate effectively dissolved necessary reagents and monomers.
- The SET-LRP process in EtLa yielded both hydrophilic and hydrophobic polyacrylates.
- Achieved precise control over polymer chain end functionality.
Conclusions:
- Ethyl lactate is an excellent green solvent for SET-LRP, enabling the synthesis of functional polyacrylates.
- This expands the range of environmentally friendly solvents for ATRP techniques.
- The findings support the use of EtLa in biomacromolecule and bioconjugate synthesis for biomedical applications.
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