Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Immunosensors.

M Aizawa1

  • 1Department of Bioengineering, Faculty of Engineering, Tokyo Institute of Technology, Japan.

Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
|August 28, 1987
PubMed
Summary
This summary is machine-generated.

This review explores immunosensor research, highlighting non-labelled and labelled types. Enzyme immunosensors show promise for enhanced sensitivity in detecting various biomarkers.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Fabrication of boron-containing apatite ceramics via reaction sintering route and their response of lymphocytes for adoptive immunotherapy.

Biomaterials and biosystems·2026
Same author

In vivo responses of β-tricalcium phosphate-based paste-like artificial bone with antibacterial properties under potentially infectious conditions using a rabbit model.

Journal of materials science. Materials in medicine·2025
Same author

Efficacy of avelumab plus axitinib versus sunitinib by numbers of IMDC risk factors and target tumor sites at baseline in advanced renal cell carcinoma: long-term follow-up results from JAVELIN Renal 101.

ESMO open·2023
Same author

Relationship between the combination of polyunsaturated fatty acids intake and psychological distress during pregnancy: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study.

Prostaglandins, leukotrienes, and essential fatty acids·2022
Same author

Gastrectomy with or without omentectomy for cT3-4 gastric cancer: a multicentre cohort study.

The British journal of surgery·2020
Same author

Thermo-, photo-, and mechano-responsive liquid crystal networks enable tunable photonic crystals.

Soft matter·2017
Same journal

The microlandscapes of tree trunks: the effect of lichen and tree-level characteristics on arthropod communities.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2026
Same journal

Centimetre-scale landscapes to assess the motion behaviour and cognition of gastropods and bivalves.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2026
Same journal

Intertidal microcosms of wave-swept rocky shores: ecological and physiological insights from a uniquely stressful environment.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2026
Same journal

Temporal and spatial variation in temperature and oxygen at the microscale: key niche axes for aquatic life.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2026
Same journal

Natural microcosms in ecology: fulfilling the promise of model systems?

Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2026
Same journal

Microbe-induced galls and plant defence: metabolite crosstalk in a co-evolutionary battle.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2026
See all related articles

Area of Science:

  • Biomedical Engineering
  • Analytical Chemistry
  • Immunotechnology

Background:

  • Immunosensors offer selective detection based on antigen-antibody interactions.
  • Research trends and future directions in immunosensor development are presented.
  • Both non-labelled and labelled immunosensor approaches are discussed.

Purpose of the Study:

  • To provide an overview of current trends and future aspects in immunosensor research and development.
  • To explore the principles and applications of non-labelled and labelled immunosensors.
  • To highlight promising advancements in immunosensor technology.

Main Methods:

  • Overview of non-labelled immunosensors utilizing immunochemical affinity for potentiometric determination.
  • Investigation of labelled immunosensors, focusing on enzyme immunosensors for enhanced sensitivity.

Related Experiment Videos

  • Discussion of bioaffinity sensors employing ligand-receptor complexes.

    • Main Results:

    • Non-labelled immunosensors have been developed for detecting syphilis antibody, blood typing, human chorionic gonadotropin (HCG), and human serum albumin.
    • Labelled immunosensors, particularly enzyme immunosensors, demonstrate enhanced sensitivity.
    • Enzyme immunosensors coupled with oxygen electrodes are effective for determining alpha-fetoprotein (AFP), HCG, IgG, and toxins.
    • Bioaffinity sensors show efficacy in determining thyroxine (T4), biotin, and insulin.

    Conclusions:

    • Immunosensor technology continues to evolve with advancements in both labelled and non-labelled designs.
    • Enzyme immunosensors represent a promising avenue for highly sensitive biomarker detection.
    • Bioaffinity sensors offer versatile applications for various analytes.