Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Scientific Method01:32

The Scientific Method

The scientific method is a detailed, empirical problem-solving process used by biologists and other scientists. This iterative approach involves formulating a question based on observation, developing a testable potential explanation for the observation (called a hypothesis), making and testing predictions based on the hypothesis, and using the findings to create new hypotheses and predictions.
Generally, predictions are tested using carefully-designed experiments. Based on the outcome of these...
The Spinal Cord01:54

The Spinal Cord

The spinal cord is the body’s major nerve tract of the central nervous system, communicating afferent sensory information from the periphery to the brain and efferent motor information from the brain to the body. The human spinal cord extends from the hole at the base of the skull, or foramen magnum, to the level of the first or second lumbar vertebra.
Spin–Spin Coupling Constant: Overview01:08

Spin–Spin Coupling Constant: Overview

In bromoethane, the three methyl protons are coupled to the two methylene protons that are three bonds away. In accordance with the n+1 rule, the signal from the methyl protons is split into three peaks with 1:2:1 relative intensities. The methylene protons appear as a quartet, with the relative intensities of 1:3:3:1.
Qualitatively, any spin plus-half nucleus polarizes the spins of its electrons to the minus-half state. Consequently, the paired electron in the hydrogen–carbon bond must have a...
Spin–Spin Coupling: One-Bond Coupling01:17

Spin–Spin Coupling: One-Bond Coupling

Coupling interactions are strongest between NMR-active nuclei bonded to each other, where spin information can be transmitted directly through the pair of bonding electrons. While nuclei polarize their electrons to the opposite spins, the bonding electron pair has opposite spins. Configurations with antiparallel nuclear spins are expected to be lower in energy. When coupling makes antiparallel states more favorable, J is considered to have a positive value. The one-bond coupling constant, 1J,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Implications of relying on manufacturer patient support programs for access to high-cost specialty and biologic medicines: a critical qualitative study.

BMJ open·2026
Same author

Theories of financialisation and health systems governance: a critical interpretative synthesis.

Health economics, policy, and law·2026
Same author

The impacts of gender and race on workplace violence against nurses and nursing assistants: A scoping review of the literature.

International journal of nursing studies·2026
Same author

Mapping the evidence on the role and impact of plastics in the context of health products and their packaging: A scoping review.

JRSM open·2026
Same author

Engaging patients in blood systems: A qualitative study on immune globulin recipient perspectives.

Social science & medicine (1982)·2026
Same author

Stigma, Scarcity and the Price of Legitimacy: Chronic Pain Advocacy and the Politics of Pharmaceutical Partnerships in Canada.

Sociology of health & illness·2026

Related Experiment Video

Updated: May 8, 2026

Comparing Bibliometric Analysis Using PubMed, Scopus, and Web of Science Databases
05:02

Comparing Bibliometric Analysis Using PubMed, Scopus, and Web of Science Databases

Published on: October 24, 2019

33.9K

'Spin' in published biomedical literature: A methodological systematic review.

Kellia Chiu1, Quinn Grundy1, Lisa Bero1

  • 1Charles Perkins Centre, Faculty of Pharmacy, The University of Sydney, Sydney, New South Wales, Australia.

Plos Biology
|September 12, 2017
PubMed
Summary

Spin in biomedical research distorts results, impacting studies and health policies. This review found spin varies by study type, often involving downplaying non-significant findings and misusing causal language.

More Related Videos

Author Spotlight: Exploring Press Needle Efficacy and Underlying Molecular Pathways
05:26

Author Spotlight: Exploring Press Needle Efficacy and Underlying Molecular Pathways

Published on: April 12, 2024

2.6K
Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
05:47

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

Published on: June 13, 2025

1.7K

Related Experiment Videos

Last Updated: May 8, 2026

Comparing Bibliometric Analysis Using PubMed, Scopus, and Web of Science Databases
05:02

Comparing Bibliometric Analysis Using PubMed, Scopus, and Web of Science Databases

Published on: October 24, 2019

33.9K
Author Spotlight: Exploring Press Needle Efficacy and Underlying Molecular Pathways
05:26

Author Spotlight: Exploring Press Needle Efficacy and Underlying Molecular Pathways

Published on: April 12, 2024

2.6K
Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
05:47

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

Published on: June 13, 2025

1.7K

Area of Science:

  • Biomedical Research
  • Scientific Reporting
  • Publication Ethics

Background:

  • Spin in scientific literature involves reporting practices that favorably distort results.
  • This can negatively influence further research, clinical practice, and health policies.

Purpose of the Study:

  • To systematically review the nature and prevalence of spin in biomedical literature.
  • To analyze the association between spin and industry sponsorship.

Main Methods:

  • Searched MEDLINE, PreMEDLINE, Embase, Scopus, and reference lists.
  • Included 35 reports investigating spin across various study designs.
  • Used narrative synthesis and meta-analyses to examine spin characteristics and funding associations.

Main Results:

  • Spin's nature and prevalence varied by study design, with clinical trials showing the greatest variability.
  • Common spin tactics included detracting from non-significant results and inappropriate causal language.
  • The association between spin and industry sponsorship was inconclusive due to data heterogeneity.

Conclusions:

  • Spin is a prevalent issue in biomedical literature with diverse manifestations.
  • Further research is needed to understand spin's impact on reader decision-making.
  • Editors and peer reviewers must be aware of spin to ensure accurate research dissemination.