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Updated: Feb 23, 2026
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Published on: August 9, 2024
Enhanced carboxylic acids production by decreasing hydrogen partial pressure during acidogenic fermentation of
Miaomiao Zhou1, Jun Zhou2, Ming Tan3
1Lab of Waste Valorization and Water Reuse, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China; University of Chinese Academy of Sciences, Beijing 100049, China.
Abstract:
In this study, the effect of reduced hydrogen partial pressure (PH2) on the generation of carboxylic acids from acidogenic fermentation of glucose was investigated. Three strategies were applied to reduce PH2: headspace removal (T1), CO2 sparging (T2) and H2:CO2 (80:20) sparging (T3). Results showed that the production of carboxylic acids in T1-T3 were 10.21, 11.64 and 12.71g/L, respectively, which were 1.04, 1.19 and 1.30-fold of that in the control (T4). The composition of carboxylic acids changed significantly in T3 with enhancement of homoacetogenesis, as more acetate and butyrate were produced comparing to the control. In addition, decreasing PH2 led to more carbon flow to carboxylic acids. Species of Clostridium became dominant in treatment T3, resulting in the shift of metabolic pathways. This study demonstrated that decreasing PH2 could increase the production of carboxylic acids, especially under the strategy of enhancing homoacetogenesis.
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