Dengue Haemorrhagic Encephalitis: Rare Case Report with Review of Literature
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Updated: Feb 23, 2026

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
Aditya Singh Kutiyal1, Chetanya Malik1, Gitika Hyanki2
1Senior Resident, Department of Internal Medicine, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India.
Abstract:
Dengue is an endemic arboviral infection prevalent especially in tropical countries including Southern and Southeast Asia. Central Nervous System (CNS) involvement in dengue infection is uncommon. Haemorrhagic encephalitis is a rare presentation in dengue. This is a case of a 58-year-old male who presented with fever, petechial rash and altered sensorium. Dengue serology IgM was reactive and MRI brain was suggestive of haemorrhagic encephalitis. Patient was managed in Intensive Care Unit (ICU) but eventually succumbed to his illness. We report this fatal outcome of a common viral infection with unusual neurological presentation to propose an association between dengue and neurotropism and the need to look at dengue infection beyond its classical features.
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