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Published on: August 8, 2025
Conduction Disturbances After Transcatheter Aortic Valve Replacement: Current Status and Future Perspectives
Vincent Auffret1, Rishi Puri1, Marina Urena1
1From University Hospital Pontchaillou, Cardiology and Vascular Disease Department, CIC-IT 804, Rennes 1 University, Signal and Image Processing Laboratory (LTSI), INSERM U1099, France (V.A.); Quebec Heart and Lung Institute, Laval University, Quebec City, Canada (V.A., R.P., C.C., T.R.-G., F.P., J.R.,-C.); and Bichat-Claude Bernard University Hospital, Paris, France (M.U.).
Transcatheter aortic valve replacement (TAVR) commonly causes conduction disturbances, often requiring pacemakers. Understanding risk factors and improving management strategies are crucial for TAVR patient outcomes.
Area of Science:
- Cardiology
- Interventional Cardiology
- Medical Devices
Background:
- Transcatheter aortic valve replacement (TAVR) is a standard treatment for aortic stenosis in high-risk patients.
- Conduction disturbances, including new-onset left bundle-branch block and atrioventricular block, are frequent TAVR complications.
- Despite technological advancements, the incidence of these conduction issues remains high.
Purpose of the Study:
- To review the incidence, predictive factors, and clinical associations of conduction disturbances post-TAVR.
- To propose management strategies for TAVR-related conduction complications.
- To address the growing need for risk mitigation as TAVR expands to lower-risk populations.
Main Methods:
- Review of existing evidence on TAVR-related conduction disturbances.
- Identification of factors associated with increased risk of pacemaker implantation.
- Analysis of the prognostic impact of new-onset conduction abnormalities.
Main Results:
- New-onset left bundle-branch block and advanced atrioventricular block are the most common complications.
- Prior right bundle-branch block, valve type, and implantation depth are key risk factors.
- These complications can negatively impact patient prognosis.
Conclusions:
- Conduction disturbances are a significant concern following TAVR, necessitating proactive management.
- Identifying high-risk patients and optimizing implantation techniques can mitigate risks.
- Developing effective strategies is essential for the safe expansion of TAVR procedures.
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