Metanephric adenoma treated with laparoscopic nephrectomy: A case report.

Area of Science:

• Nephrology
• Oncology
• Pathology

Background:

• Metanephric adenoma is an uncommon benign renal tumor.
• It shares histomorphological similarities with epithelial Wilms' tumor and papillary renal cell carcinoma.
• Accurate diagnosis is vital due to its favorable clinical outcome compared to malignant counterparts.

Purpose of the Study:

• To describe a case of metanephric adenoma.
• To highlight diagnostic challenges and treatment considerations for this rare entity.

Main Methods:

• Case report of a patient treated with laparoscopic nephrectomy.
• Analysis of contrast-enhanced computed tomography (CT) imaging.
• Immunohistochemical analysis including vimentin, Wilms' tumor 1, and various cytokeratins (CK AE1/AE3, CK56, CK34).

Main Results:

• The tumor showed subtle enhancement in the early phase of contrast-enhanced CT.
• Immunohistochemistry revealed positive vimentin and Wilms' tumor 1, with partial CK positivity, consistent with metanephric adenoma.
• The patient underwent laparoscopic nephrectomy.

Conclusions:

• Metanephric adenoma is challenging to diagnose preoperatively.
• Consideration of metanephric adenoma is essential to prevent overtreatment, such as unnecessary nephrectomy for small tumors.
• Accurate diagnosis can lead to more conservative management strategies.