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Related Experiment Video

Updated: Feb 23, 2026

Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome
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Thalamic transitory ischemic attacks presenting as Jacksonian sensory march.

Victoria Schubert1, Stephan Lauxmann1, Benjamin Bender2

  • 1Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, Eberhard-Karls University Tübingen, Hoppe-Seyler Str. 3, 72076, Tübingen, Germany.

Journal of Neurology
|September 13, 2017
PubMed
Summary
This summary is machine-generated.

Thalamic ischemia, not epilepsy, can cause spreading sensory symptoms resembling Jacksonian march. This finding highlights thalamic transient ischemic attacks as a crucial differential diagnosis for sensory seizures.

Keywords:
Jacksonian sensory marchPartial seizuresSensory strokeThalamic ischemiaTransitory ischemic attack (TIA)

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Area of Science:

  • Neurology
  • Neuroscience
  • Vascular Neurology

Background:

  • Spreading somatosensory symptoms, known as Jacksonian sensory march, are typically attributed to epileptic seizures.
  • Differentiating the cause is critical for appropriate clinical management and treatment.

Observation:

  • Three cases are presented where Jacksonian-like sensory symptoms were caused by thalamic ischemia.
  • Patients experienced recurring hemiparesthesias spreading from face to limb, with initial MRI scans being negative.
  • Repeated imaging revealed thalamic infarctions, and one case presented with isolated spreading sensory symptoms without recurrence.

Findings:

  • Thalamic ischemia can manifest as spreading sensory symptoms mimicking epileptic auras.
  • Early diagnostic imaging may not detect acute thalamic changes, necessitating repeat scans.
  • Electroencephalogram (EEG) and cardiovascular diagnostics were normal in all reported cases, ruling out other common causes.

Implications:

  • Thalamic transient ischemic attacks (TIAs) represent an important differential diagnosis for somatosensory epileptic auras.
  • Recognition of thalamic ischemia is vital for guiding distinct clinical management strategies.
  • This study expands the understanding of sensory stroke presentations beyond sudden-onset deficits.