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Updated: Feb 23, 2026

Microwave-Assisted Preparation of 1-Aryl-1H-pyrazole-5-amines
Published on: June 23, 2019
Microwave-assisted synthesis of novel hetero[5]helicene-like molecules and coumarin derivatives
Wei Lin1, Xiuxiu Hu, Shuai Song
1School of Chemistry and Environmental Engineering, Jiangsu University of Technology, Changzhou 213001, P. R. China. linwei841012@163.com.
Abstract:
A concise and efficient approach to design and synthesize hetero[5]helicene-like molecules and coumarin derivatives is reported. Intriguingly, using the same catalyst (silica sulfuric acid), and a different solvent and reaction temperature, the reaction selectively afforded hetero[5]helicene-like molecules 3 or coumarin derivatives 4. Product 4 has a highly planar geometry, and product 3 can be regarded as hetero[5]helicene-like because of its helical conformation.
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