Maximizing donor allocation: A review of UNOS region 9 donor heart turn-downs

Donna Mancini1,2, Daniel Goldstein3, Samantha Taylor4

  • 1Mount Sinai Medical Center, New York, NY, USA.

Insights

Region 9 transplant programs may miss opportunities for heart recovery. Optimizing organ selection practices could increase local heart transplants and save more lives.

Area of Science:

  • Transplantation Medicine
  • Organ Recovery
  • Cardiology

Background:

  • Heart transplantation is a critical treatment for end-stage heart failure.
  • Organ utilization rates are influenced by transplant center selection practices.
  • Region 9 transplant programs' organ selection protocols require evaluation.

Purpose of the Study:

  • To assess the optimality of organ selection practices for heart utilization in Region 9.
  • To identify potential improvements for increasing local organ recovery rates.

Main Methods:

  • Retrospective review of de-identified heart donor data from January 1, 2010, to December 31, 2013.
  • Analysis of heart donor utilization, recovery, and reasons for non-transplantation.
  • Examination of regional versus out-of-region heart offers and rejections.

Main Results:

  • Out of 537 heart donors, 321 (60%) hearts were transplanted.
  • 19% (61/321) of hearts were exported after regional turn-downs, with 43 rejected for 'quality' reasons.
  • A significant number of rejected hearts were declined by only some regional programs, suggesting potential for increased utilization.

Conclusions:

  • Transplant centers in Region 9 may have opportunities to increase local heart recovery by refining organ selection criteria.
  • Revisiting donor acceptance protocols could potentially identify additional usable organs without negatively impacting short-term outcomes.