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Mid to late S-phase replication of the nucleolus in lymphoid human Molt-4 cells
J E Celis1, P Madsen, J B Lauridsen
1Department of Medical Biochemistry, Aarhus University, Denmark.
Leukemia
|July 1, 1987
Abstract:
Indirect immunofluorescence staining of synchronized lymphoid human Molt-4 cells with proliferating cell nuclear antigen autoantibodies specific for cyclin revealed nucleolar staining only in cells in mid to late S-phase. These results together with similar earlier observations in epithelial and fibroblasts cells indicate that this organelle replicates in mid to late S-phase in cultured somatic cells.