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Published on: September 17, 2017
State of diagnosing infectious pathogens using colloidal nanomaterials
Jisung Kim1, Mohamed A Abdou Mohamed2, Kyryl Zagorovsky3
1Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario M5S 3G9, Canada; Terrence Donnelly Centre for Cellular and Bimolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada; Centre for Global Engineering, University of Toronto, Toronto, Ontario M5S 1A4, Canada.
Abstract:
Infectious diseases are a major global threat that accounts for one of the leading causes of global mortality and morbidity. Prompt diagnosis is a crucial first step in the management of infectious threats, which aims to quarantine infected patients to avoid contacts with healthy individuals and deliver effective treatments prior to further spread of diseases. This review article discusses current advances of diagnostic systems using colloidal nanomaterials (e.g., gold nanoparticles, quantum dots, magnetic nanoparticles) for identifying and differentiating infectious pathogens. The challenges involved in the clinical translation of these emerging nanotechnology based diagnostic devices will also be discussed.
