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Chagas Cardiomyopathy Presenting as Symptomatic Bradycardia: An Underappreciated Emerging Public Health Problem in
Richard Jesse Durrance1, Tofura Ullah1, Zulekha Atif1
1Department of Internal Medicine, Jamaica Hospital Medical Center, 8900 Van Wyck Expressway, Jamaica, NY 11418, USA.
Insights
Chagas cardiomyopathy (CCM) affects many in the US, often undiagnosed. Early detection in immigrants is crucial for managing this parasitic disease and preventing severe heart complications.
Area of Science:
- Infectious Diseases
- Cardiology
- Public Health
Background:
- Chagas cardiomyopathy (CCM) is a parasitic heart disease traditionally linked to endemic regions.
- An estimated 300,000 individuals in the U.S. may have CCM, with a significant portion undiagnosed.
- The influx of Latin American immigrants presents a growing challenge for CCM diagnosis in non-endemic areas.
Observation:
- A 42-year-old El Salvadoran woman presented with chest pain and syncope.
- Initial diagnosis was symptomatic sinus bradycardia, leading to pacemaker placement.
- Chagas serology was pursued due to her epidemiological background.
Findings:
- The patient was diagnosed with Chagas cardiomyopathy (CCM) in its early symptomatic stage.
- This case underscores the underrecognized prevalence of Chagas disease in the United States.
- CCM was the suspected etiology for her electrocardiographic changes.
Implications:
- Highlights the public health importance of considering Chagas disease in Latin American immigrants with cardiac symptoms.
- Emphasizes the need for improved screening and diagnostic strategies for Chagas disease in the U.S.
- Underscores the economic and clinical significance of early CCM detection and management.
Abstract:
Chagas cardiomyopathy (CCM) is traditionally considered a disease restricted to areas of endemicity. However, an estimated 300,000 people living in the United States today have CCM, of which its majority is undiagnosed. We present a case of CCM acquired in an endemic area and detected in its early stage. A 42-year-old El Salvadoran woman presented with recurrent chest pain and syncopal episodes. Significant family history includes a sister in El Salvador who also began suffering similar episodes. Physical exam and ancillary studies were only remarkable for sinus bradycardia. The patient was diagnosed with symptomatic sinus bradycardia and a pacemaker was placed. During her hospital course, Chagas serology was ordered given the epidemiological context from which she came. With no other identifiable cause, CCM was the suspected etiology. This case highlights the underrecognized presence of Chagas in the United States and the economic and public health importance of its consideration in the etiological differential diagnosis of electrocardiographic changes among Latin American immigrants. While the United States is not considered an endemic area for Chagas disease, the influx of Latin American immigrants has created a new challenge to identify at-risk populations, diagnose suspected cases, and provide adequate treatment for this disease.
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