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Updated: Feb 23, 2026

Micro-scale Engineering for Cell Biology
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Micro-scale Engineering for Cell Biology

Published on: October 1, 2007

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Introduction.

James W Putney1

  • 1The Signal Transduction Laboratory, Department of Health and Human Services, National Institute of Environmental Health Sciences - NIH, Research Triangle Park, NC, USA. putney@niehs.nih.gov.

Advances in Experimental Medicine and Biology
|September 14, 2017
PubMed
Summary
This summary is machine-generated.

This volume explores store-operated calcium entry (SOCE), a crucial cell signaling process. It details the fundamental mechanisms and historical development of SOCE research, providing an updated analysis for scientists.

Keywords:
Calcium channelsMouse modelsOraiOscillationsSTIM1Store-operated channels

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Micro-scale Engineering for Cell Biology
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Micro-scale Engineering for Cell Biology

Published on: October 1, 2007

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Area of Science:

  • Cellular Biology
  • Biochemistry
  • Physiology

Background:

  • Store-operated calcium entry (SOCE) is a fundamental mechanism for cellular calcium regulation.
  • Understanding SOCE is critical for deciphering various cell signaling pathways.
  • The field of SOCE has rapidly expanded, necessitating updated analyses.

Purpose of the Study:

  • To provide a state-of-the-art description and analysis of store-operated calcium entry (SOCE).
  • To focus on the fundamental mechanistic concepts underlying SOCE.
  • To summarize the historical development and recent advancements in SOCE research.

Main Methods:

  • Literature review and synthesis of existing research.
  • Historical analysis of the concept of store-operated calcium entry.
  • Analysis of recent work on the general function of SOCE in cell signaling.

Main Results:

  • The volume presents an updated overview of the rapidly expanding field of SOCE.
  • Fundamental mechanistic concepts underlying SOCE are detailed.
  • Recent work on the functional roles of SOCE in cell signaling is discussed.

Conclusions:

  • This work provides a comprehensive and updated resource on SOCE.
  • It highlights the foundational mechanisms and ongoing research in calcium signaling.
  • The analysis serves as a valuable reference for researchers in the field.