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Prolonged hypotension associated with Wernicke's encephalopathy.

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Area of Science:

  • Neurology
  • Internal Medicine
  • Cardiology

Background:

  • Wernicke's encephalopathy (WE) diagnosis can be challenging.
  • Hypotension is a rare but reported complication of WE.
  • Alcohol abuse is a common risk factor for WE.

Observation:

  • A 69-year-old male with alcohol abuse presented with prolonged hypotension.
  • The patient experienced 9 days of unremitting hypotension requiring vasopressor support.
  • Signs of dysautonomia, including postural blood pressure fluctuations and bradycardia, were noted.

Findings:

  • Despite thiamine treatment, the patient exhibited persistent hypotension.
  • The clinical presentation suggested a significant association between dysautonomia and WE.
  • This case highlights a prolonged hypotensive episode linked to WE and dysautonomia.

Implications:

  • This case suggests a potential link between hypotension, dysautonomia, and Wernicke's encephalopathy.
  • Clinicians should consider WE in patients with unexplained hypotension and dysautonomia, especially with a history of alcohol abuse.
  • Further research is warranted to explore the pathophysiology and management of this association.