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Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

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Ethical Issues with Genetic Testing for Tay-Sachs.

Tricia Clayton¹

¹Tricia Clayton, MSN, RN, is an assistant professor at Adventist University of Health Sciences in Orlando, Florida. She is pursuing a PhD at Barry University in Miami, Florida.

Journal of Christian Nursing : a Quarterly Publication of Nurses Christian Fellowship

|September 14, 2017

Summary

This summary is machine-generated.

Tay-Sachs disease is a devastating Jewish genetic disorder with no cure. This study explores the complex ethical issues of genetic testing for Tay-Sachs using rights-based and virtue ethics frameworks.

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Area of Science:

Medical Genetics
Bioethics

Background:

Tay-Sachs disease is a severe, fatal, inherited neurological disorder disproportionately affecting individuals of Jewish heritage.
Currently, no cure exists for Tay-Sachs disease, highlighting the critical need for preventative strategies and ethical considerations.

Purpose of the Study:

To explore the ethical complexities surrounding genetic testing for Tay-Sachs disease within the Jewish community.
To analyze Tay-Sachs disease through the lenses of rights-based ethics and virtue ethics.

Main Methods:

Literature review and ethical analysis.
Application of rights-based and virtue ethics frameworks to genetic testing dilemmas.

Main Results:

Genetic testing for Tay-Sachs disease presents multifaceted ethical challenges within the Jewish community.
Rights-based and virtue ethics offer valuable perspectives for navigating these complex issues.

Conclusions:

Ethical frameworks are essential for guiding decisions regarding Tay-Sachs disease genetic testing.
Continued dialogue and ethical consideration are crucial for supporting affected communities.