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Squamous Cell Carcinoma With Hyper-IgE Syndrome: A Case Report
Ayse S Sasihuseyinoglu1, Mustafa Yilmaz1, Derya U Altintaş1
1Departments of Pediatric Allergy and Immunology.
Journal of Pediatric Hematology/Oncology
|September 14, 2017
Summary
Hyper-immunoglobulin E syndrome (HIES) increases cancer risk. This case highlights squamous cell carcinoma (SCC) developing in a patient with HIES, emphasizing the need for vigilance.
Area of Science:
- Immunology
- Oncology
- Otolaryngology
Background:
- Hyper-immunoglobulin E syndrome (HIES) is a primary immunodeficiency characterized by recurrent infections and extremely high immunoglobulin E levels.
- Patients with HIES have an increased susceptibility to infections and malignancies.
- Squamous cell carcinoma (SCC) is a rare but documented complication in HIES patients.
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