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Isolation of Epithelial Cells from Human Dental Follicle
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Tooth resorptions are not hereditary.

Alberto Consolaro1, Débora de Almeida Bianco2

  • 1Bauru School of Dentistry, Universidade de São Paulo (Bauru/SP, Brazil). Ribeirão Preto School of Dentistry, Universidade de São Paulo (Ribeirão Preto/SP, Brazil).

Dental Press Journal of Orthodontics
|September 14, 2017
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Summary
This summary is machine-generated.

Orthodontic root resorption is not definitively linked to genetics or heredity. Methodological flaws in current studies and the inherent nature of orthodontic treatment make it difficult to attribute resorption to external factors.

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Area of Science:

  • Dentistry
  • Genetics
  • Orthodontics

Background:

  • Orthodontic treatment can lead to root resorption, a phenomenon whose etiology is debated.
  • Existing scientific evidence linking root resorption to heredity, genetic predisposition, or familial susceptibility is inconsistent.
  • Methodological limitations in current research, including diagnostic and measurement errors, hinder definitive conclusions.

Purpose of the Study:

  • To critically evaluate the scientific evidence supporting a hereditary or genetic basis for orthodontic root resorption.
  • To identify limitations in current methodologies used to study root resorption.
  • To clarify the nature of root resorption in the context of orthodontic treatment.

Main Methods:

  • Review and critique of existing scientific literature on orthodontic root resorption.
  • Analysis of diagnostic methods, including orthopantomographs and cephalograms.
  • Evaluation of sample heterogeneity and size in relevant studies.
  • Consideration of genetic and familial study methods.

Main Results:

  • Current scientific evidence does not consistently correlate orthodontic root resorption with heredity, individual predisposition, or genetic susceptibility.
  • Methodological and interpretative errors in studies, particularly in diagnosis and measurements from radiographic images, undermine findings.
  • Heterogeneous samples with varied operators, planning, and insufficient numbers limit the generalizability of results.
  • While biological events are genetically influenced, this does not equate to inherited tooth resorption; family studies do not support a direct genetic link.
  • Quantifying the exact contribution of heredity, genetics, environmental, or unknown factors to orthodontic root resorption is not feasible.

Conclusions:

  • Orthodontic root resorption should not be attributed to external factors or considered iatrogenic in most cases.
  • Root resorptions are an inherent clinical event associated with orthodontic treatment when properly planned and monitored.
  • Accurate diagnosis and planning using periapical radiography or computerized tomography, alongside consideration of predictive factors, are crucial in orthodontic practice.