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Association between coronary heart disease and erectile dysfunction in Chinese Han population
Guo-Xiang Tian1,2,3, Sheng Li1,2, Tong-Zu Liu1,2
1Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Insights
This study found no significant link between coronary heart disease (CHD) and erectile dysfunction (ED) in the Chinese Han population. Further research is needed to explore potential connections in different demographics.
Area of Science:
- Cardiology
- Urology
- Public Health
Background:
- Coronary heart disease (CHD) and erectile dysfunction (ED) are prevalent conditions.
- Investigating the association between CHD and ED is crucial for understanding cardiovascular health and male sexual function.
Purpose of the Study:
- To examine the relationship between coronary heart disease (CHD) and erectile dysfunction (ED) in the Chinese Han population.
- To determine if ED is a risk factor or indicator for CHD in this demographic.
Main Methods:
- A case-control study was conducted with 240 participants from an andrological out-patient clinic.
- Erectile dysfunction (ED) was diagnosed using the International Index of Erectile Function-5 (IIEF-5) questionnaire.
- Logistic regression models were employed to analyze the association between CHD and ED, controlling for potential confounders.
Main Results:
- A total of 56 patients with ED and 184 controls were analyzed.
- CHD prevalence was slightly higher in the ED group, but this difference was not statistically significant (OR = 1.20, 95% CI = 0.63-2.29).
- Adjusted analyses and stratified analyses by ED severity also indicated no significant association between CHD and ED.
Conclusions:
- The study suggests no statistically significant association between coronary heart disease (CHD) and erectile dysfunction (ED) in the Chinese Han population.
- The findings do not support ED as an independent predictor of CHD in this specific population.
- Further research with larger and more diverse cohorts may be warranted to confirm these results.
Abstract:
To investigate the association between coronary heart disease (CHD) and erectile dysfunction (ED) in Chinese Han population. Patients who went to the andrological out-patient clinic of our hospital between August 1, 2015 and May 1, 2016 and met all eligible criteria were enrolled in this study. The patients diagnosed as ED using self-administered International Index of Erectile Function-5 (IIEF-5) questionnaire were considered as case group and others were considered as control. The cases were categorized as mild, moderate, and severe ED. Subjects were interviewed for the history of CHD. Uni- and multivariate logistic regression models were used to calculate odds ratios (ORs) and corresponding 95% confidence intervals (CIs) using the SPSS 18.0 software. A total of 240 participants (56 ED patients and 184 controls) were enrolled. CHD prevalence was higher in cases without statistical significance (OR = 1.20, 95%CI = 0.63-2.29; p = 0.58). Results of adjusted analysis also showed a non-significantly increased risk (OR = 1.25, 95%CI = 0.55-2.85; p = 0.59). Stratified analysis by severity of ED revealed similar results. This study suggests no significant association exists between CHD and ED in Chinese Han population.
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