Fatal Deer Tick Virus Infection in Maine

Catherine E Cavanaugh1, Paul L Muscat2, Sam R Telford3

  • 1Lincoln Medical Partners Internal Medicine, Damariscotta.

Insights

Deer tick virus (DTV), a rare cause of encephalitis, can be fatal. This case followed an Ixodes scapularis tick bite and Lyme disease rash.

Area of Science:

  • Neuroscience
  • Infectious Diseases
  • Tick-borne Illnesses

Background:

  • Deer tick virus (DTV) is a lineage II genetic variant of Powassan virus.
  • DTV is a rare but serious cause of encephalitis in North America.

Observation:

  • A fatal case of DTV encephalitis is presented.
  • The patient had a documented bite from an Ixodes scapularis tick.
  • The patient also presented with an erythema migrans rash, indicative of Lyme disease.

Findings:

  • This report details a fatal encephalitis caused by Deer tick virus.
  • The case highlights a potential association between DTV infection and concurrent Lyme disease presentation following an Ixodes scapularis tick bite.

Implications:

  • This case underscores the severe neurological potential of Deer tick virus.
  • It emphasizes the importance of considering DTV in the differential diagnosis of encephalitis, especially in endemic areas with tick exposure.
  • Co-infection or sequential infection with Lyme disease may influence DTV pathogenesis or clinical presentation.

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