A comparison of dressed crab and a cadmium salt (CdCl2) as cadmium sources in rat diets

1. A long term low level exposure experiment was conducted on rats in order to determine the metabolic patterns of realistic environmental dietary levels of cadmium from different sources. 2. Male and female rats were fed a diet for 6 months with a high crab content containing 4 mg Cd/kg as organic bound cadmium from dressed crab, a diet with low crab content containing 0.2 mg Cd/kg as organic bound cadmium, a casein based diet containing 4 mg Cd/kg as cadmium chloride and a low cadmium level control diet. 3. Analysis of the cadmium levels in the kidney, liver and spleen showed that uptake from the dressed crab was only half of that from the diet fortified with cadmium chloride.