Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Seizures: Classification01:13

Seizures: Classification

1.8K
Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
1.8K
Generalized Anxiety Disorder01:30

Generalized Anxiety Disorder

821
Generalized Anxiety Disorder (GAD) is a chronic condition characterized by excessive and uncontrollable worry that persists for at least six months, significantly interfering with daily functioning. Unlike situational anxiety, which arises in response to specific stressors, GAD often occurs without a clear cause. Individuals may experience disproportionate worry about work, health, or relationships. For instance, a person might continuously fear poor health despite normal medical evaluations or...
821
Parkinson's Disease: Overview01:15

Parkinson's Disease: Overview

2.2K
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
2.2K
Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

1.5K
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
1.5K
Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

2.1K
The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
2.1K
Restless Leg Syndrome and Night Terrors01:27

Restless Leg Syndrome and Night Terrors

619
Restless Leg Syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by an uncontrollable urge to move the legs due to uncomfortable sensations. These sensations typically occur during periods of rest or inactivity, particularly when lying down or sitting, and can severely disrupt sleep.
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
619

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Read My Leads: Subject-Specific RF Hazard Assessment and Mitigation for DBS Implants in MRI.

Magnetic resonance in medicine·2025
Same author

Longitudinal Blood-Biomarker-Based Assessment of Brain Injury in Patients Undergoing Deep Brain Stimulation and Magnetic Resonance-Guided Focused Ultrasound.

Movement disorders : official journal of the Movement Disorder Society·2025
Same author

Contralateral Spread of Asymmetrical Tremor in Parkinson's Disease.

Movement disorders clinical practice·2025
Same author

Progression to Parkinson's dementia is not modulated by genetic risk variants for Alzheimer's or Parkinson's disease.

Journal of Parkinson's disease·2025
Same author

Lesioning the Subthalamic Nucleus Using Magnetic Resonance Imaging-Guided Focused Ultrasound in Parkinson's Disease: Subthalamotomy Effectively Describes the Procedure.

Movement disorders : official journal of the Movement Disorder Society·2025
Same author

Are there Predictors for the Effects of Subthalamic Versus Thalamic Lesions for the Treatment of Parkinsonian Tremor?

Movement disorders : official journal of the Movement Disorder Society·2025
Same journal

Blood Pressure Control With Clevidipine Is Associated With Hematoma Volume Reduction in Acute Hypertensive Intracerebral Hemorrhage: A Single-Center Prospective Cohort Study.

European journal of neurology·2026
Same journal

CGRP-Targeted Therapy in Vestibular Migraine-How Strong Is the Evidence?

European journal of neurology·2026
Same journal

Direct Thrombectomy vs. Combined Treatment With Intravenous Thrombolysis in the Extended Time Window: A Target Trial Emulation.

European journal of neurology·2026
Same journal

Pharmacological Treatment of Cerebellar Ataxia in Pediatric Ataxia-Telangiectasia: A Systematic Review.

European journal of neurology·2026
Same journal

Intensive Rehabilitation With Adjunctive Bilateral Anodal tDCS in Post-Stroke Dysphagia: A Multicenter Randomized Controlled Trial.

European journal of neurology·2026
Same journal

Distal Agrin (AGRN) Congenital Myasthenic Syndrome With Mitochondrial Dysfunction.

European journal of neurology·2026
See all related articles

Related Experiment Video

Updated: Feb 23, 2026

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
05:54

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor

Published on: December 13, 2017

15.0K

Is essential tremor a single entity?

F Hopfner1,2, G Deuschl1,2

  • 1Department of Neurology, Universitätsklinikum Schleswig-Holstein, Kiel Campus, Germany.

European Journal of Neurology
|September 15, 2017
PubMed
Summary
This summary is machine-generated.

Essential tremor (ET) is a common movement disorder characterized by action tremor. New classifications and research into its causes and treatments, including medication and surgery, are advancing our understanding of this condition.

Keywords:
classificationessential tremorgeneticspathophysiologyreview

More Related Videos

Behavioral Characterization of Pentylenetetrazole-induced Seizures: Moving Beyond the Racine Scale
07:35

Behavioral Characterization of Pentylenetetrazole-induced Seizures: Moving Beyond the Racine Scale

Published on: July 8, 2025

1.4K
Extraction of the EPP Component from the Surface EMG
07:16

Extraction of the EPP Component from the Surface EMG

Published on: December 16, 2009

13.0K

Related Experiment Videos

Last Updated: Feb 23, 2026

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
05:54

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor

Published on: December 13, 2017

15.0K
Behavioral Characterization of Pentylenetetrazole-induced Seizures: Moving Beyond the Racine Scale
07:35

Behavioral Characterization of Pentylenetetrazole-induced Seizures: Moving Beyond the Racine Scale

Published on: July 8, 2025

1.4K
Extraction of the EPP Component from the Surface EMG
07:16

Extraction of the EPP Component from the Surface EMG

Published on: December 16, 2009

13.0K

Area of Science:

  • Neurology
  • Movement Disorders

Background:

  • Essential tremor (ET) is a prevalent neurological condition characterized by involuntary shaking.
  • Recent classification divides ET into classical and 'ET plus' forms, aiding subtyping.
  • The underlying cause of ET remains elusive, though oscillating neural networks are implicated.

Purpose of the Study:

  • To review the current understanding of essential tremor (ET).
  • To discuss recent advancements in ET classification, etiology, and treatment options.
  • To highlight areas for future research in essential tremor.

Main Methods:

  • Literature review of essential tremor research.
  • Analysis of new classification systems for ET.
  • Summary of current and emerging treatment modalities for ET.

Main Results:

  • ET is now classified into classical and 'ET plus' subtypes.
  • Electrophysiology suggests oscillating central nervous system networks are involved.
  • Pathology indicates possible adaptive brain changes, particularly in the cerebellum.
  • Genetics research has identified ET syndromes in other genetic diseases.
  • Effective treatments include medications (propranolol, primidone, topiramate) and surgical options (DBS, gamma-knife, MRI-guided focused ultrasound).

Conclusions:

  • Further research integrating cohort studies and basic science is needed to elucidate ET etiologies.
  • Aging-related tremor may account for a significant number of clinical cases.
  • Despite presumed diverse etiologies, ET is clinically viewed as relatively uniform.