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[Fibromuscular dysplasia and hypertension : beyond renal arteries]

Grégoire Wuerzner1, Caroline Krieger2, Julie Bouchardy3

  • 1Département de médecine, Service de néphrologie et d'hypertension, CHUV, 1011 Lausanne.

Revue Medicale Suisse
|September 15, 2017
PubMed

Insights

Fibromuscular dysplasia (FMD) is a rare arterial disease affecting medium-sized arteries, often discovered incidentally. Early diagnosis and a multidisciplinary approach are crucial for managing FMD complications like stenosis and dissections.

Area of Science:

  • Vascular Medicine
  • Radiology
  • Genetics

Background:

  • Fibromuscular dysplasia (FMD) involves arterial wall abnormalities in medium-sized arteries.
  • These abnormalities can cause arterial stenosis, dissections, or aneurysms.
  • FMD is likely underdiagnosed and often found incidentally during imaging.

Purpose of the Study:

  • To review current knowledge on fibromuscular dysplasia.
  • To highlight the need for standardized, multidisciplinary patient work-up.
  • To improve understanding and management of FMD.

Main Methods:

  • Non-systematic review of existing literature.
  • Illustration with a relevant clinical case.
  • Discussion of diagnostic and management strategies.

Main Results:

  • FMD presents with diverse arterial pathologies, including stenosis, dissection, and aneurysm.
  • Diagnosis is often incidental but can be prompted by symptoms of poor organ perfusion.
  • A standardized, multidisciplinary approach is essential for optimal patient care.

Conclusions:

  • Fibromuscular dysplasia requires a comprehensive and collaborative approach for effective management.
  • Further research is needed to enhance understanding of FMD pathogenesis and epidemiology.
  • Standardized work-up protocols will improve patient outcomes and disease knowledge.

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