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[A new furan-2-carboxylic acid from stem bark of Cassia alata]
Ling Zhou1,2, Wei Dong1,2, Yue-de Wang2
1College of Chemistry and Environment, Yunnan Minzu University, Kunming 650500, China.
Abstract:
A new furan-2-carboxylic acid, 5-[3-(hydroxymethyl)-4,5-dimethoxyphenyl]-3-methylfuran-2-carboxylic acid(1),has been isolated from the bark of Cassia alata by using various chromatographic techniques. It displayed cytotoxicity against NB4, A549, SHSY5Y, PC3 and MCF7 cell lines with IC₅₀ values of 2.5, 1.2, 2.2, 3.6 and 1.9 μmol•L⁻¹, respectively.

