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Angle Closure Glaucoma: Treatment01:28

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Related Experiment Video

Updated: Feb 22, 2026

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
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Postvitrectomy macular hole undergoing delayed closure after 28 months.

Rutul Patel1, Mahesh Gopalakrishnan1, Bindu Rajesh1

  • 1Department of Vitreo-Retina, Giridhar Eye Institute, Cochin, Kerala, India.

Indian Journal of Ophthalmology
|September 15, 2017
PubMed
Summary

A 70-year-old male experienced a macular hole (MH) after surgery for vitreomacular traction syndrome. Spontaneous closure of the MH occurred after 28 months, improving vision without further intervention.

Area of Science:

  • Ophthalmology
  • Retinal Surgery
  • Macular Diseases

Background:

  • Vitreomacular traction syndrome can lead to serious complications, including macular holes.
  • Macular holes (MH) are full-thickness retinal defects that can impair central vision.

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